Recent Advances in Nanozymes: From Matters to Bioapplications

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First Author:Yongjian Ai

Correspondence Author:Xiaoping Liang, Hong-bin Sun, Hongbo Xin, Qionglin Liang

Co author:Ze-Nan Hu

Journal:Advanced Functional Materials

Issue:14

Volume:32

Impact Factor:18.5

DOI number:10.1002/adfm.202110432

Affiliation of Author(s):Department of Chemistry, Northeastern University

Teaching and Research Group:物理化学

Place of Publication:Germany

Abstract:The manufacture of bionic materials to simulate the natural counterpartshas attracted extensive attention. As one of the subcategories of biomimeticmaterials, the development of artificial enzyme is intensive pursuing. As akind of artificial enzyme, nanozymes are dedicated to solve the limitationsof natural enzymes. In recent years, attributed to the explosive developmentof nanotechnology, biotechnology, catalysis science, computational designand theory calculation, research on nanozymes has made great progress.To highlight these achievements and help researchers to understand thecurrent investigation status of nanozyme, the state-of-the-art developmentin nanozymes from fabrication materials to bioapplications are summa-rized. First different raw materials are summarized, including metal-based,metal-free, metal-organic frameworks-based, and some other novel matters,which are applied to fabricate nanozymes. The different types of enzymes-like catalytic activities of nanozymes are briefly discussed. Subsequently,the wide applications of nanozymes such as anti-oxidation, curing diseases,anti-bacteria, biosensing, and bioimaging are discussed. Finally, the currentchallenges faced by nanozymes are outlined and the future directions foradvancing nanozyme research are outlooked. The authors hope this reviewcan inspire research in the fields of nanotechnology, chemistry, biology, mate-rials science, and theoretical computing, and can contribute to the develop-ment of nanozymes.

Document Code:WOS:000730537200001

Discipline:Natural Science

First-Level Discipline:Chemistry

ISSN No.:1616-301X

Translation or Not:no