Copper(I)-catalyzed reaction of diaryl buta-1,3-diynes with cyclic amines: an atom-economic approach to amino-substituted naphthalene derivatives

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First Author:Hongbin Sun

Correspondence Author:Ruimao Hua

Co author:Hongbin Sun, Xiaoli Wu,Ruimao Hua 

Journal:Tetrahedron Letters

Issue:34

Volume:52

Impact Factor:1.5

DOI number:10.1016/j.tetlet.2011.06.046

Affiliation of Author(s):Department of Chemistry, Tsinghua University

Teaching and Research Group:物理化学

Place of Publication:ENGLAND

Abstract:1,4-Diaryl-1,3-butadiynes react with cyclic amines, such as pyrrolidine, piperidine, and morpholine in the presence of a catalytic amount of CuCl to afford amino-substituted naphthalene derivatives with good to high yields. The new catalytic procedure provides an atom-economic, one-pot synthetic method for the synthesis of naphthalene derivatives from easily available 1,4-diaryl-1,3-butadiynes.

Key Words:Cuprous chloride, Cyclic amine ,Diaryl buta-1,3-diyne,Naphthalene derivatives

Document Code:WOS:000293987000012

Discipline:Natural Science

First-Level Discipline:Chemistry

Page Number:4408-4411

ISSN No.:0040-4039

Translation or Not:no