第一作者：Yiming Wang

通讯作者：Qionglin Liang,Hong-Bin Sun

合写作者：Tian Haimeng,Li Hong,Deng Xinchen,Zhang Qiao,Ai Yongjian,Sun Zejun,Wang Yu,Liu Lei,Hu Zenan, Zhang Xinyue,Guo Rongxiu,Xu Wenjuan

发表刊物：Acs Applied Materials & Interfaces

期号：6

卷号：14

影响因子：8.3

DOI码：10.1021/acsami.1c22256

教研室：物理化学

刊物所在地：Energy & Fuels

摘要：Cascade reactions take advantage of step-saving and facileoperation for obtaining chemicals. Herein, catalytic hydrogenation ofnitroarene coupled condensation with β-diketone to afford β-ketoenaminesis achieved by an integrated nanocatalyst, Pd-e@UiO-66. The catalyst hasthe structure of an acid-rich metal−organic framework (MOF), UiO-66-encapsulated electron-rich Pd nanoparticles, and it reconciles the electron-effect contradiction of cascade catalytic reactions: catalytic hydrogenationrequires an electron-rich catalyst, while condensation requires electron-deficient Lewis acid sites. The catalyst showed good activity, highchemoselectivity, and universal applicability for the synthesis of β-ketoenamines using nitroarenes. More than 30 β-ketoenamines havebeen successfully prepared with up to 99% yield via the methodology ofrelay catalysis. The catalyst exhibited excellent stability to maintain itscatalytic performance for more than five cycles. Furthermore, we conducted an in-depth exploration of the reaction mechanism withtheoretical calculations

关键字：cascade synthesis,β-ketoenamines,hydrogenation of nitroarenes,relay catalysis,reconciliation of electron-preference conflict,atmospheric H2

论文编号：WOS:000758112600001

学科门类：理学

一级学科：化学

页面范围：7949-7961

ISSN号：1944-8244

是否译文：否