First Author:Ruihang Jiang

Correspondence Author:Hong-bin Sun, Zhangpei Chen

Co author:Shuang Li, Kun Zhan, Junjie Zhou, Lei Liu, Kai Zhang, Qionglin Liang

Title of Paper:Synthesis of tetrazoles, triazoles, and imidazolines catalyzed by magnetic silica spheres grafted acid

Journal:Synthesis Communications

Issue:20

Volume:48

Impact Factor:2.1

DOI Number:10.1080/00397911.2018.1510007

Institution:Department of Chemistry, Northeastern University

Teaching and Research Group:物理化学

Place of Publication:UNITED STATES

Summary:The magnetically separable catalysts are used in the synthesis of N-containing heterocycles, including tetrazoles, triazoles, and imidazolines. The magnetic silica sphere grafted sulfonic acid (MSS-SO3H) is suitable for the synthesis of 1,2,3-triazole via the cycloaddition of nitroalkene with NaN3, whereas the zinc-modified silica sphere catalyst (MSS-SO3Zn) is more suitable for the synthesis of tetrazoles. The MSS-SO3Zn catalyst also works well for the synthesis of 2-substituted imidazoline via the condensation of nitriles with ethylenediamine. Both of the MSS-SO3H and MSS-SO3Zn catalysts can be recovered easily by a magnet, and they can be reused without further tedious activation.

Key Words:Magnetically separable; silica sphere; imidazolines; triazoles; tetrazoles; heterocycles

Document Code:WOS:000452641700004

Discipline:Natural Science

First-Level Discipline:Chemistry

Page Number:2652-2662

ISSN:1532-2432

Translation or Not:No