First Author:Hong-bin Sun

Correspondence Author:Xinlin Deng

Co author:Dong Li , Weiping Xie 

Title of Paper:Catalytic Cyclization of 2,3-Dibromopropionates with Benzyl Azides to Afford 1-Benzyl-1,2,3-triazole-4-carboxylate: The Use of a Nontoxic Bismuth Catalyst

Journal:HETEROCYCLES

Issue:3

Volume:92

Impact Factor:0.8

DOI Number:10.3987/com-15-13371

Teaching and Research Group:物理化学

Place of Publication:JAPAN

Summary:We synthesized 1,2,3-triazoles via the cyclization of 2,3-dibromopropionates with benzyl azides. Bismuth chloride is an efficient catalyst, and the reaction is accelerated by weak bases such as sodium acetate. A variety of functional groups are compatible with this catalytic protocol, and it takes advantage of oxygen stable catalyst and substrates because the reactive dibromides are saturated.

Document Code:WOS:000374081000002

Discipline:Natural Science

First-Level Discipline:Chemistry

Page Number:423-430

ISSN:0385-5414

Translation or Not:No