First Author:Hongbin Sun

Correspondence Author:Ruimao Hua

Co author:Hongbin Sun, Xiaoli Wu,Ruimao Hua 

Title of Paper:Copper(I)-catalyzed reaction of diaryl buta-1,3-diynes with cyclic amines: an atom-economic approach to amino-substituted naphthalene derivatives

Journal:Tetrahedron Letters

Issue:34

Volume:52

Impact Factor:1.5

DOI Number:10.1016/j.tetlet.2011.06.046

Institution:Department of Chemistry, Tsinghua University

Teaching and Research Group:物理化学

Place of Publication:ENGLAND

Summary:1,4-Diaryl-1,3-butadiynes react with cyclic amines, such as pyrrolidine, piperidine, and morpholine in the
presence of a catalytic amount of CuCl to afford amino-substituted naphthalene derivatives with good to
high yields. The new catalytic procedure provides an atom-economic, one-pot synthetic method for the
synthesis of naphthalene derivatives from easily available 1,4-diaryl-1,3-butadiynes.

Key Words:Cuprous chloride, Cyclic amine ,Diaryl buta-1,3-diyne,Naphthalene derivatives

Document Code:WOS:000293987000012

Discipline:Natural Science

First-Level Discipline:Chemistry

Page Number:4408-4411

ISSN:0040-4039

Translation or Not:No